AOD-9604 — Advanced Fat-Metabolizing Peptide (Fragment 176-191 Derivative)
AOD-9604 is a peptide fragment of human growth hormone (HGH), engineered to mimic the hormone’s fat-burning region without triggering muscle-building or insulin effects.
This makes it a research-grade compound of high interest for studies on fat metabolism, weight loss, and metabolic regulation — offering a targeted, lipolytic profile with excellent safety and stability.
Scientific Overview
AOD-9604 represents the modified amino acid sequence of HGH (residues 176-191), the region directly responsible for stimulating lipolysis and inhibiting lipogenesis.
Unlike full-length HGH, AOD-9604 does not affect IGF-1 levels or glucose metabolism, making it an ideal research tool for studying fat-specific metabolic pathways.
- Promotes fat breakdown (lipolysis)
- Inhibits new fat cell formation (lipogenesis)
- ⚙️ Improves metabolic rate and energy utilization
- Preserves lean mass during caloric deficit
- May aid in sleep quality and recovery through improved GH signaling
Product Specifications
| Compound: | AOD-9604 (Fragment 176-191) |
| Sequence: | Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Gly-Phe-Tyr-Ser-Thr-Gly-Ser-Gly-Glu |
| CAS Number: | 221231-10-3 |
| Purity: | ≥ 98% (HPLC) |
| Form: | Sterile lyophilized peptide powder |
| Appearance: | White/off-white crystalline |
⚗️ Mechanism of Action
AOD-9604 targets the beta-adrenergic lipolytic pathway, specifically increasing the breakdown of stored triglycerides into free fatty acids while suppressing the storage of new fat.
It is believed to exert its effects through localized activation of adipocyte lipase enzymes without systemic GH or IGF-1 side effects.
In animal and human trials, AOD-9604 demonstrated strong fat-reduction capabilities, particularly in abdominal and visceral fat regions.
Reconstitution & Storage
- Reconstitution: Add Bacteriostatic Water (recommended 1–2 mL per vial).
Alternatives: Sterile Water (short-term) or 0.6% Acetic Acid (extended preservation). - ❄️ Storage: Store lyophilized vials refrigerated (2–8 °C). After reconstitution, refrigerate and use within 20 days.
Research Applications
- Metabolic & weight-management studies
- Adipose tissue reduction models
- Muscle preservation during caloric restriction
- Obesity, glucose tolerance, and energy balance research
- Potential synergistic use with Tesamorelin, CJC-1295, or Ipamorelin
⚠️ Disclaimer
For Research Use Only. This compound is not intended for human consumption, diagnostic, or therapeutic use.
All descriptions and data are for educational purposes only. Researchers must be 18 years or older.
All materials are handled in sterile, certified laboratory environments.
By purchasing or accessing this material, you acknowledge compliance with all applicable research regulations.
