Kisspeptin-10 (Peptide Hormone) — Research-Grade
Kisspeptin-10 is a naturally occurring peptide that plays a crucial role in stimulating the release of gonadotropin-releasing hormone (GnRH), which in turn activates the entire reproductive hormone cascade — including luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This makes it a key signaling molecule in the regulation of testosterone, estrogen, fertility, and overall reproductive function.
Scientific Overview
Kisspeptin is a neuropeptide derived from the KISS1 gene, first identified for its role in suppressing metastasis — but later found to be a potent activator of the hypothalamic-pituitary-gonadal (HPG) axis. By binding to the GPR54 receptor (also called KISS1R), it triggers the release of GnRH, which then stimulates the pituitary to release LH and FSH — the hormones responsible for sex steroid production.
- Promotes natural LH & FSH secretion
- Encourages endogenous testosterone or estrogen release
- Supports fertility and reproductive health
- May help “restart” hormonal signaling post-cycle
- Enhances libido and sexual responsiveness in both males & females
Product Specifications
| Compound: | Kisspeptin-10 |
| Sequence: | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ |
| CAS: | 374684-63-4 |
| Appearance: | Lyophilized powder (white/off-white) |
| Purity: | ≥ 98% (HPLC) |
| Form: | Peptide vial, sterile lyophilized |
Reconstitution & Storage
- Reconstitution: Reconstitute with Bacteriostatic Water (recommended).
Alternative options: Sterile Water (for short-term use) or 0.6% Acetic Acid (for extended stability). - ❄️ Storage: Store lyophilized vial in a cool, dry place. Once reconstituted, refrigerate at 2–8°C.
⚙️ Research Applications
Kisspeptin-10 has been extensively studied in relation to:
- Hypothalamic stimulation and hormonal signaling
- Fertility enhancement and reproductive health
- Post-cycle recovery support (PCT adjunct)
- Libido and sexual function optimization
- Regulation of pituitary-gonadal axis feedback
⚠️ Disclaimer
For Research Use Only. Not for human consumption, diagnostic, or therapeutic use. All data provided is for educational and informational purposes only. Users must be 18 years or older. By accessing this material, you acknowledge that you are purchasing for legitimate research purposes under applicable laws. Product is produced and handled under sterile conditions in a certified facility.
